First, who use sheer force conk, second who will let you to do mach punch 2 time's. People once went under subs will do freezy dry and kill or lower it, so your first mach punch will be to remove subs, second to do some dmg if he is not dead from the first one
Same applies for calm mind clefable, every player will switch to something that can handle it. Imo kyurem can stay but only if is without sub.